For years it was hypotethised that there is a link between diabetes and Alzheimer's disease. But, as the latest researches point out, both illnesses got something in common: poor blood sugar management and insulin resistance. Despite the sugar being present in almost everything we eat or drink (yes, even bread, yogurts, cereals, you name it, it is there), our body tolerance for sugar is somewhere around 15-20 grams of single carbohydrates per day. Per day, i said, and keep in mind that just one energy drink with reduced sugar has 24 grams of it. There is also the not so well explained issue about high and low glycaemic index foods. Let's start with this first.
The higher the glycaemic index is (do not think only about sugar, the starch also has something to do with this - white bread, white rice, potatoes, baking goods) the larger amounts of insulin our pancreas will secrete into the bloodstream, to lower the blood sugar. If this happen too often, our cells will start to resist to the insulin signalling too much blood sugar, in the same way you got used in a very noisy environment (eventually). The noise is there (blood sugar in our case), but you stop reacting too it. And a high level of blood sugar is damaging our body in so many ways. (Find more about this in this article).
Well known effects of the insulin resistance are type 2 diabetes, fatty liver, metabolic syndrome, but also AD (Alzheimer's disease). There are many pathways that are affected by the insulin resistance. To start with the insulin binding to the insulin receptors, triggering the survival of the neurons, you can only imagine what will happen if this trigger is drastically decreased by the high insulin levels, present most of the time in our bloodstream. Another way to mess up with our nervous system is via the insulin-degrading enzyme (IDE) used to get rid on the insulin, but, surprise, also used to get rid of the amyloid beta (one of the main issues in AD). Because, as we know already, higher levels of amyloid-beta equals full blown AD.
As the insulin resistance is just a result, the cause being chronically high blood sugar levels, let's see how this is wreaking havoc in our body. The glucose can attack easily to many proteins, interfering with their usual functions. The common blood test to check diabetes called HbA1c is measuring one of these overused proteins - hemoglobins changed to produce advanced glycation end products (AGE). As these proteins trigger our immune system, raising inflammation (one of the risk factors in AD), they are also binding to their own receptor (AGE receptors of RAGE), triggering inflammation even further. Shall we add to the list? Yes, there is more, AGE molecules form free radicals, which in turn can damage almost anything they touch, even DNA and any cell membranes. The additionally damage the blood vessels (less nutrients to go to the brain) and negatively alter the blood-brain barrier.
The main blood tests to monitor these risk factors are fasting insulin level (ideally 4.5 microIU/ml or less), the HbA1c test (ideally under 5.6%) and the fasting glucose ( ideally between 70-90 mg/dl, but not more than that). How you manage this? Learning about diabetes management is a good idea, as everything that is recommended for a type 2 diabetes, it will also work for healthy individuals or pre-diabetes condition.
******
On another turn of events, i am a bit dissapointed of the cryptofaucet.com, as they paid my first transaction, and stopped working after, and the second one is on wait for at least a week. If it is keep staying stuck i will take it out the link from my list.
******
Kucoin made a cheeky move, with staking for their own coin KCS (Kucoin Shares), but they give you only POL tokens for staking, and POL value was decreasing lately, so i do not like it, it is much better to keep thew KCS in the main account for the 2 staking bonuses paid there which are on the range of 4-5%. My opinion only.
My crypto-related links
Exchanges
Binance( good for staking/savings ) - link here
Kucoin( good for staking/savings ) - link here
Coinbase( ideal for beginners )- link here
Investments
BlockFi (decent interest rates, but less choices than Celsius) - link here
Eobot( mining/wallet )- link here
Celsius.network (very good rates of interests and monthly promo codes for free cryptocurrencies )- link here
Coinbundle(investing in crypto bundles) - link here
Wallets for multiple cryptocurrencies
Coinpot - link here (microwallet for all Moon faucets, Bitfun and Bonusbitcoin)
Atomic wallet - link here (microwallet for Publish0x DAI, BAT and Loopring)
Sphere wallet (for Horizen, combined with the faucet for extra bonus) - link here
Free crypto (faucets)
Bitfun( 3 min countdown - automatically deposit to Coinpot wallet ) - link here
Bonusbitcoin( 15 min countdown - automatically deposit to Coinpot wallet ) - link here
Moon Bitcoin ( 5 min countdown - automatically deposit to Coinpot wallet ) - link here
Moon Bitcoin Cash ( 5 min countdown - automatically deposit to Coinpot wallet ) - link here
Moon Litecoin ( 5 min countdown - automatically deposit to Coinpot wallet ) - link here
Moon Dogecoin ( 5 min countdown - automatically deposit to Coinpot wallet ) - link here
Moon Dash ( 5 min countdown - automatically deposit to Coinpot wallet ) - link here
Horizen faucet ( 20 hours countdown - automatically deposit to Sphere wallet ) - link here
Tezos faucet ( 7 days countdown - automatically deposit to Coinbase or Binance wallet ) - link here
Tron faucet (24 hours countdown) - link here
Others
Publish0x blog (Free BAT, DAI and Loopring for reading/writing - can combine with Atomic wallet) - link here
Brave browser (Free BAT for using it, based on paid ads, very good AdBlocker and high speed) - link here
Disclaimer: This text it is also re-published on my personal blog, in here.
