Dear Readers,
This is indeed a major milestone on the battle against cancer.
Before looking into the cancer vaccine, we will have a brief overview of cancer related to this post.
What is Cancer ?
Cells refuse to listen to speech at a specific location, Proliferate in large numbers and with Excessive amount of Achieving growth; Refusing to die when one's time is up and despite the resistance of the body. This will be getting green and continuing to grow out of control. Self-absorption of nutrients in the body by increasing blood flow.
Once established in a particular place, it invades the nearby places and then mixes with the blood and spreads to distant organs as well.
Cancer is from the nature of average cells in contrast, our cells become our villains.
How do our cells, which have been functioning well until then, change like this?
It is caused by changes in the genes in those cells.
Usually in cells, genes that control cancer are naturally present.
Also, many genes are operating inside the cells to prevent the growth of one cell wall beyond the outer wall of another cell, to kill itself when it reaches maturity, and to prevent unnecessary proliferation.
These are what prevent us from getting cancer.
However, persistent injuries at one site—for example, lung injury from cigarette smoke, oral injury from tobacco, or injuries from certain viruses—can cause cervical cancer.
The genes that protect against this cancer are affected.
Hence cancer occurs.
Now the altered genes work in cancer cells.
They act like on all proliferating cancer cells from within.
This is how it works
Cancer cells make proteins.
This is where our article begins.
For cancer cells to thrive and grow
Cancer genes are important
Next
A protein in cancer cells that is needed to build cancer cells...
Using our technology
If these genes are blocked from doing their job or
If we destroy the specific proteins that cancer cells make, can we destroy tumors as well?
That technology is called "m RNA" (m RNA or MESSENGER RNA) technology.
What is this messenger RNA?
DNA is located in the nucleus of every cell.
Receiving messages from DNA itself and carrying it to ribosomes to stimulate the production of proteins
It is the function of messenger RNA.
Scientists have been researching for the past thirty years
They learned the technology of synthetically producing messenger RNA.
Research has been going on for more than ten years using messenger RNA technology to find drugs to treat cancer.
Scientists are the knowledge gained through those researches
They demonstrated success using messenger RNA technology in vaccine development during the Covid pandemic.
Indeed the covid pandemic has arrived
Until the success of messenger RNA technology vaccines, including Pfizer and Moderna, the world of medical science did not pay much attention to this technology.
However, now it is a triumph of hard work
The 2023 Nobel Prize was awarded to Katalin Carrico and Drew Weisman for their "discovery of messenger RNA technology".
The main reason they were awarded the prize was that their invention saved lakhs of lives during the Covid pandemic.
So how can this technology be used to prevent cancer and viral infections?
The spike protein of the pandemic coronavirus / or proteins produced by cancer cells
Pack the messenger RNA and coat lipids around it with nanotechnology
When injected into the body, Messenger RNAs containing the protein of this virus/protein of cancer cells by the cells of the body will be consumed to cells.
The imported mRNA tells the cell to make the same proteins as the one it brought in.
Our body recognizes these proteins as "antigens".
These antigens the dendritic cells in our immune system are well aware of and able to resist them
Teaches T cells.
T-cells seek out and destroy all of these proteins.
Also, in the future, we will look for similar proteins wherever they appear in our body.
Thus, in a study conducted by Moderna using messenger RNA technology, two out of ten people with head and neck cancer were completely cured and the cancer tumor size shrank in five people.
Through this technology, a small piece of a cancerous tumor is taken and sent for testing to extract the proteins it has produced
If they are packaged into messenger RNA and injected into the body
A special immune system is created against that particular protein and the cancer cells containing that protein are destroyed.
The technology has advanced enough to package and deliver 34 oncogenic proteins in such messenger RNA vaccines.
Using this technology, the vaccine developed by Russia has been administered to animals (PRE CLINICAL STUDIES) and found to completely cure cancer tumors and metastasis.
Currently, after testing this technology on humans, they are planning to provide it as a vaccine to the public in 2025.
How can that be?
Yes.. for example some of the most common cancers in Russia
For example
- Lung cancer
- Prostate cancer
- Breast cancer
Analyze common proteins made by cancer cells, such as blood cancers, and package them into a messenger RNA vaccine.
When offering to the public, If these cancers occur in the future, the immune system will kill those cells at an early stage.
In 2021, the FDA granted emergency pre-approval for BNT111, a vaccine against the skin cancer melanoma, using the same technology.
In May 2024, an mRNA vaccine against cancer caused by the Epstein Barr virus was approved.
Since this type of vaccine can be developed very simply and quickly, it is possible to prepare a special vaccine (PRECISION MEDICINE) suitable for noir within a few weeks of the diagnosis of cancer.
Messenger RNA technology is set to dominate cancer and infectious disease prevention within the next ten years for sure!
Let’s hope for the best and this to be a success one!