Boston Bruins - Pittsburgh Penguins 

Tricky one. I think both teams are looking strong at the moment. I could definitely see both teams take this one away. I wouldn't be surprised at all to see this go to overtime. The Pens have won three games in a row. They also have a brutal record at home (19-3-2). I will let that decide here. Pittsburgh wins! 

New Jersey Devils - Philadelphia Flyers 

The Devils are just waiting for the season to end now. Philly is pretty much out of the playoff race, but they have played pretty well recently. I think it's easy to pick out a team here. Philadelphia wins! 

Buffalo Sabres - New York Rangers 

The Sabres have played pretty well recently, but so has the Rangers, and the latter are the better team by far. It's not a given who will win, but Buffalo is the underdog here. New York wins! 

Columbus Blue Jackets - Tampa Bay Lightning 

Tampa has struggled lately, and they have a less than impressive record against Columbus. The latter are completely down under right now though. The Bolts shouldn't lose here. Tampa Bay wins! 

In summary, my winners are: 

Pittsburgh Penguins 
Philadelphia Flyers 
New York Rangers 
Tampa Bay Lightning